Toxoplasmosis and Campylobacteriosis in Sheep

Risks, Impacts, and the Benefits of Vaccination with Toxovax® and Campyvax®

Reproductive losses are one of the most costly and frustrating challenges in sheep production. Two of the most important and preventable causes of abortion and poor lambing performance in New Zealand flocks are toxoplasmosis and campylobacteriosis. Both diseases are widespread, often underdiagnosed, and capable of causing significant hidden losses long before an abortion storm becomes obvious.

Vaccination with Toxovax® and Campyvax® is a proven and cost-effective strategy to protect ewe fertility, lift lambing percentages, and improve flock productivity.

Toxoplasmosis in Sheep

What Is Toxoplasmosis?

Toxoplasmosis is caused by the protozoan parasite Toxoplasma gondii, which is shed in the faeces of cats. Sheep become infected by ingesting contaminated pasture, silage, hay, grain, or water.

Once introduced, toxoplasmosis often becomes a persistent farm problem, as oocysts survive in the environment for long periods.

Effects on Reproduction

The impact of infection depends on the stage of pregnancy:

  • Early pregnancy: Embryonic loss and reabsorption, resulting in dry ewes or late lambers

  • Midpregnancy: Abortion, mummified foetuses

  • Late pregnancy: Stillbirths or weak lambs that die soon after birth

Without vaccination, toxoplasmosis can cause abortion rates of 30–50% in naïve flocks during outbreaks.

Campylobacteriosis in Sheep

What Is Campylobacteriosis?

Campylobacteriosis is a bacterial disease caused mainly by Campylobacter fetus fetus and Campylobacter jejuni. The organisms are spread through contaminated feed, water, aborted material, and direct contact between sheep.

Many ewes become silent carriers, allowing infection to persist on farms for years.

Effects on Reproduction

Campylobacter infection can cause:

Early embryonic loss (dry ewes or poor scanning results)

  • Lateterm abortions

  • Stillbirths

  • Weak, nonviable lambs

Abortion storms can result in lamb losses of up to 30% in susceptible flocks.

Benefits of Vaccination

Why Vaccinate?

Management strategies alone are often insufficient once these diseases are established. Vaccination provides reliable, flockwide protection and prevents both visible abortion storms and hidden reproductive losses.

Toxovax® – Protection Against Toxoplasmosis

Key Benefits

  • Singleshot vaccination provides longlasting immunityProtects against abortion storms

  • Average 3% increase in lambing percentage

  • Significant reduction in dry ewes

Dosage and Administration

  • Dose: 2 mL per ewe

  • Route: Intramuscular (IM) injection

  • Schedule:

    • Single dose at least 3–4 weeks before mating

    • Only for nonpregnant ewes

  • Booster: Not required in most systems (long-duration immunity)

Important Safety Notes

  • Do not vaccinate pregnant ewes

  • Live vaccine – special care required during handling

  • Not to be handled by pregnant women or immunocompromised persons

Campyvax® – Protection Against Campylobacteriosis

Key Benefits

  • Prevents abortion and perinatal losses

  • Improves scanningtomarking performance

  • Increases lambing percentage by an average of up to 9%, even on farms without obvious abortions

  • Reduces the impact of hidden reproductive losses

Dosage and Administration

  • Dose: 1 mL per ewe (NZ Campyvax®4 formulation)

  • Route: Subcutaneous (SC) injection in the neck

  • Primary Course:

    • Two doses 4–8 weeks apart, completed before mating

  • Booster:

    • Annual booster prior to each mating season

Bringing It Together: A Practical Vaccination Strategy

Most NZ sheep systems benefit from using both vaccines, as toxoplasmosis and campylobacteriosis often occur together and cause overlapping production losses.

Typical premating plan:

  • Maiden and mixed-age ewes:

    • Toxovax®: once (nonpregnant, prior to mating)

    • Campyvax®: two-dose primary, then annual boosters

Conclusion

Toxoplasmosis and campylobacteriosis remain two of the leading infectious causes of reproductive failure in sheep. Because losses often occur silently, vaccination is best viewed as productivity insurance rather than outbreak control.

Strategic use of Toxovax® and Campyvax® results in fewer dry ewes, more lambs on the ground, and stronger flock performance year after year.

For more information, please visit sheepvax.co.nz.

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